Pediatrics & Therapeutics
Open Access
ISSN: 2161-0665
ISSN: 2161-0665
Hamza Malik
Pakistan
Case Report
Maintenance Treatment of Childhood Primary Angiitis of Central Nervous System with Aspirin and Azathioprine
Author(s): Muhammad Akbar Malik, Naseer Ahmad and Hamza MalikMuhammad Akbar Malik, Naseer Ahmad and Hamza Malik
Objectives: We aimed to assess the efficacy and safety of Aspirin and Azathioprine in prevention of recurrence of childhood primary angiitis of central nervous system (cPACNS) after induction therapy with intravenous pulse Methylprednisolone/ Immunoglobulin, and describe long-term neurological outcomes in a cohort of children with this disorder. Study type: Case series Methods: The cohort comprised of consecutive patients diagnosed as having childhood primary angiitis of central nervous system (cPACNS), based on clinical and vascular imaging findings, including identification of arterial stenosis on conventional angiography or Magnetic Resonance (MR) angiography. Over the period of 2 years, 68 children with cPACNS were admitted, who presented within 14 days of onset of the symptoms. Patients with ischemic infarcts were initially treated in conjunction with Heparin/ Oral Anticoagulant .. Read More»
DOI:
10.4172/2161-0665.1000174