Pediatrics & Therapeutics
Open Access
ISSN: 2161-0665
+44 7868 792050
ISSN: 2161-0665
+44 7868 792050
Eman Muhammad Abdelsalam
Mansoura Faculty of Medicine,
Egypt
Research Article
Magnetic Resonance Imaging Versus Serum Ferritin Levels in Detection of Liver and Cardiac Iron Overload in Non-Transfusion Dependent Thalassemia
Author(s): Mohamed Mahmoud Sarhan, Mohamed Mohamed El-Asmy, Eman Muhammad Abdelsalam and Ghada Magdy MohamedMohamed Mahmoud Sarhan, Mohamed Mohamed El-Asmy, Eman Muhammad Abdelsalam and Ghada Magdy Mohamed
Background: MRI is now established as the non-invasive modality of choice for the diagnosis of liver iron overload. Recently, it has been used to estimate myocardial iron overload in adult patients with acquired anemia.
Objective: To assess the value of gradient-echo T2* in monitoring and screening of both liver and cardiac iron overload in non-transfusion dependent thalassemia (NTDT).
Material and methods: This prospective study was conducted on children with mean age 11 years. Measurements were obtained in the same 1.5 MRI examination, followed by calculation with the reference spread sheet and then, the results were compared to the standard serum ferritin levels.
Results: The s.. View More»
DOI:
10.4172/2161-0665.1000324