Journal of Proteomics & Bioinformatics
Open Access
ISSN: 0974-276X
+44 1223 790975
ISSN: 0974-276X
+44 1223 790975
Dariusz Leszczynski
Laippatie 4, 00880 Helsinki
Finland
Research Article
Proteomic Analysis of the Response of Human Endothelial Cell Line EA.hy926 to 1800 GSM Mobile Phone Radiation
Author(s): Reetta Nylund, Hanna Tammio, Niels Kuster and Dariusz LeszczynskiReetta Nylund, Hanna Tammio, Niels Kuster and Dariusz Leszczynski
Background: We have earlier shown that exposure of human endothelial cell line EA.hy926 to 900 MHz GSM mobile phone radiation causes changes in the expres sion of numerous proteins. Here, we have examined the ef fects of 1800 MHz GSM mobile phone signal on the proteome of the same cell line.
Results: EA.hy926 cells were exposed for one hour to 1800 MHz GSM signal, simulating mobile phone talkin g conditions, at an average specific absorption rate (SAR) of 2.0 W/kg at 37±0.3°C. Sham samples were produced simultaneously in the same conditions but without t he radiation exposure. Cells were harvested immediatel y after 1-hour exposure to the radiation, and proteins were extr a cted a nd sepa r a ted using 2-dimensiona l electrophoresis (2DE). In total, 10 experimental re .. View More»
DOI:
10.4172/jpb.1000105