Journal of Proteomics & Bioinformatics
Open Access

Brett A Chromy

Biography

Dr. Brett Chromy is an Adjunct Assistant Professor in the Department of Pathology and Laboratory Medicine (DOPLM) and serves as the Associate Director of the Clinical Proteomics Initiative affiliated with the department. He also has a Visiting Researcher position at the Center for Biophotonics Science and Technology (CBST). Dr. Chromy has specialized in proteomic technologies throughout his career, leading a biodefense proteomics initiative since 2002 when he joined LLNL as a postdoctoral researcher and then moved into a Biomedical Scientist appointment in 2004. Since joining UC Davis, he has led proteomic projects involving biomarker discovery in human biofluids and proteomic characterization of diverse sample types, including cancer stem cells. In addition, his research interests involve the search for medical countermeasures to combat category A select agent pathogens and drug-resistant pathogens of military concern, including broad spectrum antimicrobial drugs and vaccine development. Dr. Chromy earned his Ph.D. in biochemistry from Northwestern University, where he studied protein biochemistry of the amyloid β protein, the cause of Alzheimer’s disease. He co-discovered a new form of the protein and holds several patents on the discovery and application of these toxic, oligomeric structures (called ADDLs). Earlier work at the University of Chicago, where he graduated with a BA in biology, involved the examination of neuronal membrane receptor proteins (serotonin and opioid), where he developed his long-standing interest in biophysical approaches to study protein structure/function.

Research Interest

Proteomics, Biochemistry, Alzheimer's disease

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