Journal of Proteomics & Bioinformatics

Journal of Proteomics & Bioinformatics
Open Access

ISSN: 0974-276X

+44 1223 790975

Anurag Payasi

Anurag Payasi
Venus Medicine Research Centre, Hill Top Industrial Estate,
Bhatoli Kalan, Baddi, H.P.-173205

  • Research Article
    Rising Antimicrobial Resistance of Pseudomonas aeruginosa Isolated from Clinical Specimens in India
    Author(s): Manu Chaudhary and Anurag PayasiManu Chaudhary and Anurag Payasi

    The rising antibiotic resistance against commonly used drugs is of great concern. Drug susceptibility testing and Polymerase Chain Reaction (PCR) assay were used to determine the antibiotic susceptibility patterns and prevalence of genes encoding extended-spectrum-β-lactamases (ESBLs) and metallo-β-lactamases (MBLs) among 515 isolates of Pseudomonas aeruginosa isolated from various clinical specimens. Susceptibility of isolates to seven antibiotics was tested using disc diffusion method according to the guidelines defined by Clinical Laboratory Standard Institute. Isolates showing resistance to any of the two cephalosporins (ceftriaxone, ceftazidime and cefotaxime) were subjected to PCR for the prevalence of ESBL and MBL gene characterization. Out of the 515 isolates, 235 (45.63%) were considered as ESBL positive; 87 (16.89%) were MBL positi.. View More»
    DOI: 10.4172/jpb.1000253

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