Portulaca oleracea is globally used both as a vegetable and as an herb for medical and therapeutic purposes; hence the need to investigate its phytonutrients. The aim of this study was to evaluate the effects of different drying methods (hot-air drying, microwave drying and freeze-drying) on the color, phytochemicals content and antioxidant capacity of purslane leaves. The fresh purslane leaves had high contents of total phenolics (1447.59 mg GAE/ 100 g) and flavonoids (5011.87 mg QE/ 100 g) on dry weight basis. They exhibited high antioxidant capacity (53.23% and 147.78 μmol trolox/ 100 g) measured by DPPH and ABTS assay, respectively. Chromatic coordinates (L*, a* and b*) as well as total color difference (ΔE) were affected by drying methods. Drying methods caused a significant decrease in total phenolics, total flavonoids and antioxidant capacity of purslane leaves. Drying by hot-air at 50ºC and freezedrying had the lowest adverse effects on antioxidant capacities of purslane leaves while microwave drying cannot be a competitive process for preserving antioxidants and antioxidant capacity of purslane leaves. The changes in the antioxidant capacity due to the drying methods were positively correlated with the content of phenolics (R2= 0.9043- 0.9885). Therefore, it can be suggested that special care should be taken when processing method is selected for the exploration of purslane leaves.