Improvement of Lentigines by Oral Crocetin Administration and Examination of Its Mechanism of Action

Haifeng Zeng¹, Lihao Gu¹, Naofumi Umigai², Reiko Maruya³, Takashi Koikeda⁴ and Kazuhisa Maeda^1*

¹Bionics Program, Tokyo University of Technology Graduate School, Hachioji City, Tokyo, Japan

²Riken Vitamin Co., Ltd., Chiyoda-ku, Tokyo, Japan

³SOUKEN Co., Ltd., Minato-ku, Tokyo, Japan

⁴Shiba Palace Clinic, Minato-ku, Tokyo, Japan

^*Corresponding Author: Kazuhisa Maeda, Bionics Program, Tokyo University Of Technology Graduate School, 1404-1 Katakuramachi, Hachioji City, Tokyo 192-0982, Japan, Tel: +81-42-637-2442, Fax: +81426372442