Journal of Clinical and Experimental Ophthalmology
Open Access
ISSN: 2155-9570
ISSN: 2155-9570
Ziya Ayhan
Turkey
Research Article
The Evaluation of Choroidal Vascular Changes Associated with Vascular Dysregulation in Patients with Multiple Sclerosis Using Enhanced Depth Imaging Optical Coherence Tomography
Author(s): Omer Karti, Ziya Ayhan, Eyyup Karahan, Dilek Top Karti, Mahmut Kaya, Asli Koskderelioglu, Mutesem Gedizlioglu, Mehmet Ozgur Zengin and Tuncay KusbeciOmer Karti, Ziya Ayhan, Eyyup Karahan, Dilek Top Karti, Mahmut Kaya, Asli Koskderelioglu, Mutesem Gedizlioglu, Mehmet Ozgur Zengin and Tuncay Kusbeci
Purpose: To evaluate the choroidal thickness (CT) in patients with Multiple Sclerosis (MS) using enhanced depth imaging optical coherence tomography (EDI-OCT) and comparing it with healthy subjects. Material/Methods: Sixty-four eyes of 32 patients with MS (22 women, 10 men, mean age: 37.5 ± 8.21 years) were enrolled in this study. Their choroidal thickness was measured using EDI-OCT, and compared with healthy subjects. CT was measured at fovea and at four extrafoveal points. Results: The mean subfoveal choroidal thickness was 327.01 ± 64.60 μm in MS patients and 365.3 ± 99.14 μm in controls ( p=0.019 ). Significant differences were found at points temporal 500 μm, temporal 1000 μm and nasal 500 μm to the fovea between patients and control group ( p=0.018, 0.003 and 0.03, respectively). Conclusions: Patients with MS had thinner choroids when compared.. View More»
DOI:
10.4172/2155-9570.1000534