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Journal of Drug Metabolism & Toxicology

Journal of Drug Metabolism & Toxicology
Open Access

ISSN: 2157-7609

Xiaoyan Jiang

Publications
  • Review Article
    Drug Metabolism and Pharmacokinetics of Organosulfur Compounds from Garlic
    Author(s): Cuicui Gao, Xiaoyan Jiang, Haina Wang, Zhongxi Zhao and Weihong WangCuicui Gao, Xiaoyan Jiang, Haina Wang, Zhongxi Zhao and Weihong Wang

    The medicinal activities of garlic organosulfur compounds identified include antitumor, antimicrobial, antifungal, antivirus, anti-atherosclerosis, blood lipids and sugar lowering, antithrombotic, anti-hypotension and immune modulation effects. These multi-targeted new agents may be especially promising since recently developed highly specific anti-cancer agents as well as other disease treatment drugs have failed to live up to the expectations. Despite more than one thousand articles have been published on garlic organosulfur compounds, the drug metabolism and pharmacokinetics of these compounds behind their health-promoting effects are still poorly understood. In this review, we will focus on metabolic pathways and pharmacokinetics of organosulfur compounds from garlic, which is intended to fill the void on the important aspect for further nutraceutical and pharmaceutical product de.. View More»

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