Journal of Drug Metabolism & Toxicology

Journal of Drug Metabolism & Toxicology
Open Access

ISSN: 2157-7609

Wen-Xing Ding

Wen-Xing Ding
Toxicology and Therapeutics, The University of Kansas Medical Center,
MS 1018 3901 Rainbow Blvd, Kansas City, 66160

  • Editorial
    Autophagy in Toxicology: Defense against Xenobiotics
    Author(s): Wen-Xing DingWen-Xing Ding

    Autophagy is a lysosomal degradation pathway that can degrade cellular proteins and damaged organelles to maintain cellular homeostasis. It is generally agreed that autophagy is a cellular protective mechanism against cell death, but in certain cases, it has been reported that autophagy also contributes to cell death. Although the role of autophagy in toxicology has not been extensively studied, I here discuss the current knowledge regarding the role of autophagy in xenobiotic-induced cell death. I also discuss the role of autophagy in the regulation of redox homeostasis and tumorigenesis... Read More»
    DOI: 10.4172/2157-7609.1000e108

    Abstract PDF

Relevant Topics