Journal of Clinical and Experimental Ophthalmology
Open Access
ISSN: 2155-9570
ISSN: 2155-9570
Vanessa Vasquez
Tanzania
Case Report
Ranibizumab Monotherapy in Neovascular Age-Related Macular Degeneration with Pigment Epithelial Detachment
Author(s): Abumere Akinwale, Moss Fenberg, Vanessa Vasquez and Deeba HusainAbumere Akinwale, Moss Fenberg, Vanessa Vasquez and Deeba Husain
Purpose: To evaluate the effect of ranibizumab monotherapy in patients with neovascular age related macular degeneration (AMD) associated with a pigment epithelial detachment (PED).
Methods: A retrospective chart review of neovascular AMD with associated PED treated using initial three monthly doses of ranibizumab followed by as needed dosing. The response to treatment was assessed by evaluating changes in visual acuity and central macular thickness (CMT) by ocular coherence tomography. The total ranibizumab injections needed was also assessed.
Results: A total of 14 eyes from 12 patients were included in this study. The average follow up period was 35 months (range 17 - 62 months). The mean logMAR visual acuity decreased from 0.596 (snellen ~ 20/80) to 1.018 (snellen ~20/200), however this was not statistically signific.. View More»