Journal of Clinical and Experimental Ophthalmology
Open Access

Sylvia L. Groth

Publications

• Research Article
  Effectiveness of Needling Revision with Mitomycin-C for Failing Blebs
  Author(s): Sylvia L. Groth and William Eric SponselSylvia L. Groth and William Eric Sponsel
  
  This surgical technique study was designed to evaluate the efficacy of surgical needling revision using Mitomycin-C to restore filtering function in scarred or encapsulated filtering blebs, and thereby minimize reliance on adjunctive medications. Twenty-eight eyes of 23 consecutive patients were studied, all having undergone operating room based bleb revisions for inadequate IOP-control during 2008-10. The standard needling procedure was performed as described with our previous data set, now using a 1-minute intra-bleb cannulation of 0.6 ml of 0.4 mg/ml MMC rather than multiple postoperative subconjunctival 5-fluorouracil injections. Outcome measures were IOP, number of antiglaucoma medications, and acuity. Both mean IOP reduction and decrease in anti-glaucoma medications at all four measured time intervals (1 week, 1 month, 2 months, 6 months) post-operatively were highly significant.. View More»
  DOI: 10.4172/2155-9570.S4-006

  Abstract PDF

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