Journal of Clinical and Experimental Ophthalmology
Open Access
ISSN: 2155-9570
ISSN: 2155-9570
Onur Özyurt
Turkey
Research Article
Structural and Functional Evaluation of Glaucomatous Neurodegeneration from Eye to Visual Cortex using 1.5T MR Imaging: A Pilot Study
Author(s): Kaya N Engin, Bülent Yemisci, Sibel Töreyen Bayramoglu, Nurten Turan Güner, Onur Özyurt, Esin Karahan, Cengizhan Öztürk and Penbe ÇagatayKaya N Engin, Bülent Yemisci, Sibel Töreyen Bayramoglu, Nurten Turan Güner, Onur Özyurt, Esin Karahan, Cengizhan Öztürk and Penbe Çagatay
Aim: Glaucoma is an optic neuropathy and glaucomateus damage proceeds from retinal ganglion cells to brain. A better understanding of retrobulbar damage will enable us to develop more efficient strategies and a more accurate understanding of glaucoma. We evaluated retrobulbar glaucomatous damage with favorable techniques for 1.5T MR imaging.Material and methods: Five glaucoma cases and one healthy subject are included. Diffusion tensor MR imaging and functional MR images were taken with 1.5T MR. Correlation of optic nerve and corpus geniculatum laterale diffusion tensor MR parameters with eye findings were statistically evaluated.Results: Optic nerve damage and cortical hypofunction were shown with diffusion tensor MR and functional MR imaging, respectively. Correlations of the apparent diffusion coefficient with mean devi.. View More»
DOI:
10.4172/2155-9570.1000341