Journal of Clinical and Experimental Ophthalmology
Open Access
ISSN: 2155-9570
ISSN: 2155-9570
Nicola Pescosolido
Italy
Research Article
Neovascularization in Alkali-Burned Rabbit Cornea
Author(s): Nicola Pescosolido, Andrea Barbato, Dario Rusciano and Carlo CavallottiNicola Pescosolido, Andrea Barbato, Dario Rusciano and Carlo Cavallotti
Objective: To study the neovascularization in regenerating and proliferating corneal cells following a standard alkali injury in rabbit eye.
Methods: Three and six weeks after the creation of an alkali burn in the center of the right cornea of six albino rabbits, the animals were killed and histological sections from the cornea of both eyes were stained, photographed and studied for a possible formation of a neovascularization. The photographs were examined using the Quantimet image analyzer (Leica) and statistical analysis of the data was performed.
Results: Sections of the injured cornea showed the formation of neovessels in the epithelial and superficial stromal layers. The neovascularization is present after 3 weeks of the corneal injury. After 6 weeks from the corneal alkali burn, neovessels are increased.
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DOI:
10.4172/2155-9570.1000417