Anesthesia & Clinical Research
Open Access

Nicola Muscatiello

Publications

• Research Article
  A Prospective, Randomized Comparative Study of Respiratory and Hemodynamic Monitoring during Colonoscopy using Remifentanyl Versus Propofol/Fentanyl
  Author(s): Giuseppina Mollica, Lucia Mirabella, Savino Spadaro, Nicola Muscatiello, Nicola Della Valle, Gabriele Racanelli, Girolamo Caggianelli, Pasquale Del Vecchio, Carmine Panella, Enzo Ierardi, Michele Dambrosio and Gilda CinnellaGiuseppina Mollica, Lucia Mirabella, Savino Spadaro, Nicola Muscatiello, Nicola Della Valle, Gabriele Racanelli, Girolamo Caggianelli, Pasquale Del Vecchio, Carmine Panella, Enzo Ierardi, Michele Dambrosio and Gilda Cinnella
  
  Objective: We hypothesized that remifentanil continuous infusion during colonoscopy in spontaneous respiration may give benefits in terms of quality of sedation and recovery compared to propofol, and that patients’ ventilatory drive and consciousness could be accurately evaluated by the continuous measurement of end-tidal CO2 (EtCO2), and of Bispectral Score (BIS) respectively. Methods: One-hundred and eighty patients scheduled for colonoscopy were randomized in two groups: 76 patients were included in Groupcontrol (propofol 0.5 mg/kg bolus plus infusion 1 mg/kg/h) and 78 patients in Gruopremi (0.5 mcg/Kg/1 min bolus plus infusion 0.08 mcg/kg/min, progressively reduced to 0.03 mcg/kg/min). Cardiovascular and respiratory variables were measured before induction and every 3 min throughout the procedure. Sedation level was estimated by BIS .. View More»
  DOI: 10.4172/2155-6148.1000381

  Abstract PDF

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