Journal of Drug Metabolism & Toxicology
Open Access
ISSN: 2157-7609
ISSN: 2157-7609
Nedime Şahinoğlu Keşkek
Turkey
Research Article
The Effects of N-acetylcysteine in Patients with Amanita phalloides Intoxication
Author(s): Ahmet Akin, Sakir Özgür Keskek, Didem Aydin Kiliç, Mehmet Aliustaoğlu and Nedime Şahinoğlu KeşkekAhmet Akin, Sakir Özgür Keskek, Didem Aydin Kiliç, Mehmet Aliustaoğlu and Nedime Şahinoğlu Keşkek
Objectives: Mushroom intoxication with Amanita phalloides has a high incidence throughout the world. Treatment for this intoxication is similar in different centers, but N-acetylcysteine is rarely used. In this study, we aimed to investigate the effects of N-acetylcysteine treatment in patients with Amanita phalloides intoxication.
Methods: A total of 40 patients with Amanita phalloides intoxication were included in this retrospective study. The study group consisted of 24 patients who were administered N-acetylcysteine in addition to the standard regimen; the control group consisted of 16 patients who were treated only with the standard treatment. Treatment results and biochemical measurements of groups were compared. Results: According to the biochemical measurements, it was found that patients in the control group were affected more seriousl.. Read More»
