Applied Microbiology: Open Access
Open Access
ISSN: 2471-9315
+44 1300 500008
ISSN: 2471-9315
+44 1300 500008
Mohamed Abdel-Samiee
Department of Hepato-Gastroenterology, National Liver Institute,
Egypt
Research Article
Magnitude of Clostridium Difficile Infection in Hospitalized Egyptian Patients with Liver Cirrhosis
Author(s): El-Sayed Tharwa, Mohamed Abdel-Samiee, Ashraf Abou-Gabal and Azza Abd El-AzizEl-Sayed Tharwa, Mohamed Abdel-Samiee, Ashraf Abou-Gabal and Azza Abd El-Aziz
Background and Aim: Watery diarrhea is the cardinal clinical symptom of Clostridium Difficile infection that causes a spectrum of manifestations ranging from asymptomatic carrier state to severe fulminant disease with toxic megacolon. The basis for symptomatic responses range is related to host and pathogen factors. We studied the prevalence of Clostridium Difficile infection in hospitalized cirrhotic patients and its possible risk factors.
Patients and methods: This study was carried out on 200 cirrhotic patients admitted to National Liver Institute hospital divided into 2 groups: 100 asymptomatic patients and 100 patients with diarrhea. Direct stool toxin detection was done using an assay named RIDASCREEN® Clostridium Difficile Toxin A/B test; an enzyme immunoassay (EIA) for the qualitative determi.. View More»
DOI:
10.4172/2471-9315.1000127