Journal of Clinical and Experimental Ophthalmology
Open Access
ISSN: 2155-9570
+44 1223 790975
ISSN: 2155-9570
+44 1223 790975
Maja Pauk-Gulic
University Eye Hospital ‘Svjetlost’, Heinzelova 39, 10000 Zagreb,
Croatia
Research Article
Successful Treatment of Postkeratoplasty Fungal Keratitis with Topical and Intrastromal Voriconazole
Author(s): Maja Pauk-Gulic, Nikica Gabric, Alma Bišcevic, Adi Pašalic and Iva DekarisMaja Pauk-Gulic, Nikica Gabric, Alma Bišcevic, Adi Pašalic and Iva Dekaris
Objective: Corneal grafts have a major risk of fungal keratitis due to long-term local and sometimes systemic steroid/antibiotic use. The aim of this study was to evaluate the efficacy of intrastromal voriconazole as a therapeutic adjunctive for the management of fungal keratitis in corneal graft.
Design: Presentation of two cases of fungal keratitis occurring after corneal transplantation and treated at the University Eye Hospital “Svjetlost”.
Participants and Methods: Two cases of postkeratoplasty fungal keratitis are presented in the study. Both patients had decreased visual acuity, eye redness and severe pain occurring at 10 and 12 months after uneventful corneal transplantation. They were still receiving steroid/antibiotic topical treatment to protect their corneal graft. Patients presented with a stroma.. View More»
DOI:
10.4172/2155-9570.1000393