Reproductive System & Sexual Disorders: Current Research
Open Access
ISSN: 2161-038X
+44 1300 500008
ISSN: 2161-038X
+44 1300 500008
Liudmila Korkina
Founder and CEO, Centre of Innovative Biotechnological Investigations “Nanolab",
197 Vernadskiy Pr., 119571 Moscow
Serbia
Research Article
Clinical and Laboratory Assessment of Supplementation with Marine Collagen Peptides and Selected Antioxidants in Men with Mild-to-Moderate Erectile Dysfunction
Author(s): Zaira F. Kharaeva, Ismail A. Miziev, Diana H. Shorova, Michael Papacharalambous, Chiara De Luca and Liudmila KorkinaZaira F. Kharaeva, Ismail A. Miziev, Diana H. Shorova, Michael Papacharalambous, Chiara De Luca and Liudmila Korkina
Objectives: Notwithstanding great progress in the management of erectile dysfunction (ED) by phosphodiesterase inhibitors, safety concerns hinder their routine use in men with mild-to-moderate forms. Several plant-derived supplements have been proven acceptable substituents of conventional anti-ED drugs. Most anti-ED drugs/supplements act through nitric oxide (NO)-dependent molecular pathways, due to NO-induced smooth muscle relaxation of the local Corpus cavernosum vessels. A randomised single-blind self-controlled clinical investigation recently showed that dietary supplementation with marine collagen peptides (MCP) in combination with selected antioxidants remarkably enhanced nitrite/nitrate plasma levels along with skin rejuvenation and general energising (hormesis-like) effects. This pilot study was designed to reveal possible clinical action of .. View More»
DOI:
10.4172/2161-038X.1000179