Gonadotropin releasing hormone also known as luteinizing hormone-releasing hormone and luliberin, as well as gonadorelin is produced and secreted by specialised nerve cells in the hypothalamus of the brain. It is a trophic peptide hormone responsible for the release of follicle-stimulating hormone and luteinizing hormone from the anterior pituitary.
During childhood, the levels of gonadotrophin-releasing hormone are extremely low, but as puberty approaches there is an increase in gonadotrophin-releasing hormone which triggers the onset of sexual maturation. When the ovaries and testes are fully functional, the production of gonadotrophin-releasing hormone, luteinising hormone and follicle stimulating hormone are controlled by the levels of testosterone (in men) and oestrogens (eg, oestradiol) and progesterone (in women). If the levels of these hormones rise, the production of gonadotrophin-releasing hormone decreases and vice versa.
Related Journals of Gonadotropin-releasing hormone
Journal of Autacoids and Hormones, Endocrinology & Metabolic Syndrome, Reproductive Biology and Endocrinology, Best Practice and Research in Clinical Endocrinology and Metabolism, Clinical Pediatric Endocrinology, Endocrine Journal, Endocrine development.