Reproductive System & Sexual Disorders: Current Research
Open Access
ISSN: 2161-038X
ISSN: 2161-038X
Khalid Abd Aziz Mohamed
Benha
Egypt
Research Article
Calcium Dobesilate versus Cabergoline for Prevention of Ovarian Hyper
Stimulation Syndrome
Author(s): Ahmed Samy Saad and Khalid Abd Aziz MohamedAhmed Samy Saad and Khalid Abd Aziz Mohamed
Background: OHSS (Ovarian Hyper stimulation Syndrome) is the most serious iatrogenic complication of ovulation induction. The pathophysiology of OHSS is characterized by increased capillary permeability, leading to leakage of fluid from the vascular compartment, with third space fluid accumulation and intravascular dehydration.
Objective: This study aimed to evaluate the effectiveness of Calcium dobesilate (CaD) in comparison to the dopamine agonist cabergoline in preventing OHSS in high-risk patients undergoing assisted reproductive technique cycles.
Methods: In this study, 200 women who were at high risk for developing OHSS were randomly allocated into two groups. Group A (Calcium dobesilate group, 100 women) and group B (Cabergoline group, 100 women). All patients were assessed weekly after retrieval and for 8 w.. View More»