Anesthesia & Clinical Research
Open Access

Khaled Yassen

Publications

• Research Article
  Effect of Target-Controlled Infusion of Propofol-Fentanyl versus Desflurane in Cirrhotic Patients Undergoing Major Hepatic Resection with Transoesophageal Doppler Monitoring A Randomized Control Study
  Author(s): Khaled Yassen, Amr Farouk Safty, Mohamed Hussien Abdullah, Ragab Saad Beltagy, Fatma Ahmed Mahmoud and Ahmed Mohamed AttarKhaled Yassen, Amr Farouk Safty, Mohamed Hussien Abdullah, Ragab Saad Beltagy, Fatma Ahmed Mahmoud and Ahmed Mohamed Attar
  
  Background and aim: The choice of anaesthetic agents is important for cirrhotics undergoing liver resection. Aim is to compare Target Controlled Infusion (TCI) Propofol-Fentanyl versus Desflurane (Des) on recovery, hemodynamics monitored with Transoesophageal Doppler (TED), the effect on hepatocellular, kidney functions and economics. Patients and methods: Prospective randomized controlled study, 50 patients (Child A) divided equally. In (Des) group induction with fentanyl (1microgram/kg), propofol (2 mg/kg) and rocuronium (1 mg/kg) and maintenance with Desflurane. In (TCI) group the Propofol blood target concentration (Ct) for induction was set at 4 μg/min and Fentanyl infusion was set at 3 μg/kg for 30 seconds , 2 μg/kg/h for 30 min, 1.5 μg/kg/h from 31-150 min, and 1 μg/kg/h until 30 min before end. Both propofol and fentanyl maintained with Navigator pharmacokinetic.. View More»
  DOI: 10.4172/2155-6148.1000485

  Abstract PDF

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