Journal of Clinical and Experimental Ophthalmology
Open Access
ISSN: 2155-9570
+44 1223 790975
ISSN: 2155-9570
+44 1223 790975
Kenneth O Simbiri
Molecular Medicine & Center for Biotechnology,
431, 1900 N 12th Street, Philadelphia, PA 19122
Tanzania
Case Report
Bilateral Lacrimal Gland Mantle Cell Lymphoma: A Case Report and Review of the Literature
Author(s): Cristiana Bellan, Polito Maria Sole, Barbarino Marcella, Polito Ennio, Kenneth O Simbiri, Giacomina Massaro-Giordano and Antonio GiordanoCristiana Bellan, Polito Maria Sole, Barbarino Marcella, Polito Ennio, Kenneth O Simbiri, Giacomina Massaro-Giordano and Antonio Giordano
Background: In this report we will describe a case of mantle cell lymphoma (MCL) in the conjunctiva and underlying clinical, histologic, immunological and genetic findings jointly with review of current literature.
Case presentation: Here we report a case of MCL presenting as bilateral conjunctival masses of a period of over four in a 70-year-old man.
Method and results: Histological examination revealed a proliferation of monotonous small-to-medium-sized lymphoid cells with cleaved nuclei in the subconjunctiva. The lymphoid infiltrate expressed CD20, CD5, BCL-2, cyclin D1, and the transcription factor SOX11.
Conclusion: We suggest a more focused approach to differential diagnosis of this cancer, as MCL is a more aggressive disease than other entities. Due to the rarity of this lymphoma a multidis.. View More»
DOI:
10.4172/2155-9570.1000615