Journal of Clinical and Experimental Ophthalmology
Open Access
ISSN: 2155-9570
ISSN: 2155-9570
Jan Lešták
Charles University Faculty of Medicine in Hradec Králové,
Czech Republic
Research Article
High Tension Glaucoma and Normal Tension Glaucoma in Brain MRI
Author(s): Jan Lešták, Jaroslav Tintera, Martin Kyncl, Zuzana Svatá and Pavel RozsívalJan Lešták, Jaroslav Tintera, Martin Kyncl, Zuzana Svatá and Pavel Rozsíval
Introduction: Functional and structural changes of the central nervous system corresponding to high tension glaucoma (HTG) and normal tension glaucoma (NTG) were studied.
Methods: In four patient groups, 80 eyes in 40 patients were examined. First group of 30 patients had three types of HTG: 10 with primary open angle glaucoma (POAG), 10 with pigmentary glaucoma (PG) and 10 of the monitored patients had pseudoexfoliative glaucoma (PEXG). The last patient group consisted of 10 patients with NTG. Comparison of the visual field, GDx, macular volume, PERG and PVEP was performed with the control group consisting of 40 eyes in 20 healthy subjects of comparable age and refraction.
From the group of patients with HTG and NTG, we further studied functional brain changes using functional magnetic resonance imaging (fMRI). We examined 9 patie.. View More»
DOI:
10.4172/2155-9570.1000291