Journal of Clinical and Experimental Ophthalmology
Open Access
ISSN: 2155-9570
+44 1223 790975
ISSN: 2155-9570
+44 1223 790975
Geeta Shroff
Nutech Mediworld, H-8, Green Park Extension, New Delhi-110016
India
Case Report
Use of Human Embryonic Stem Cells in the Treatment of Age-Related Macular Degeneration
Author(s): Geeta ShroffGeeta Shroff
Introduction: Age-related macular degeneration (AMD), a progressive neurodegenerative condition, primarily affects the retinal pigmented epithelium resulting in degeneration of photoreceptors. The previously available antivascular endothelial growth factor and retinal translocation do not appear to be valuable in restoring the lost vision. Now-a-days, cell-based therapy has gained a momentum in the treatment of AMD. Case Report: We report a case of 73-yr old female with AMD who was treated with human embryonic stem cells (hESCs). hESC therapy consisted of different treatment phases (T1, T2, T3) with gap phases in-between. In T1 phase (8-Week to 12-Week), hESCs were administered via intramuscular route twice daily (0.25 ml), intravenous route every 10 days (1 ml) and supplemental routes every 7 days (1-5 ml). Following the treatment, the patient showed improvement in the focus, was abl.. View More»
DOI:
10.4172/2155-9570.1000446