Journal of Sleep Disorders & Therapy
Open Access

Francesco Spirito

Biography

Laboratory of Genetic, “Vito Fazzi”, ASL Lecce, Italy. Frequency of Human Leukocyte Antigens, Plasminogen Activator Inhibitor-1 and Methylenetetrahydrofolate Reductase Gene Polymorphisms in Obstructive Sleep Apnea-Hypopnea Syndrome with or without Pulmonary Artery Hypertension

Research Interest

His laboratory is interested in the characterization of the multiple roles that the extracellular matrix plays during vertebrate organogenesis, and in congenital and acquired disorder of the connective tissue. We are currently focused on the characterization of pathophysiological mechanisms in Marfan syndrome and scleroderma using a combination of in vivo and ex vivo approaches. His long-term goal is to identify suitable biological targets for therapeutic interventions against these life-threatening diseases.

Relevant Topics