Bipolar Disorder: Open Access
Open Access
ISSN: 2472-1077
+44 1478 350008
ISSN: 2472-1077
+44 1478 350008
Fornaro M
Italy
Commentary
Second Generation Long-Acting Antipsychotics in the Treatment of Bipolar Disorder: A Clinical Viewpoint
Author(s): De Berardis D, Fornaro M, Orsolini L, Vellante F, Carano A, Valchera A, Tomasetti C, Martinotti G and Di Giannantonio MDe Berardis D, Fornaro M, Orsolini L, Vellante F, Carano A, Valchera A, Tomasetti C, Martinotti G and Di Giannantonio M
Bipolar Disorder (BD) is a severe, chronic and disabling condition. The gold standard of treatment is lithium, but the introduction of Second Generation Long-Acting Antipsychotics (SGA-LAIs) has been addressed several problems in the administration of oral SGAs in BD such as the patient’s adherence to the treatment. The aim of this commentary was to provide an overview of the use of SGA-LAIs in the treatment of BD. All considered, the use of SGA-LAIs such as Risperidone Long-Acting and Aripiprazole Long-Acting may have an important impact on the maintenance treatment of BD both in monotherapy or in association with mood stabilizers. In our opinion, the treatment with a SGA-LAI should be initiated as early as possible in BD, especially when non-adherence is suspected. Moreover, as personality disorders (PD) and BD may often coexist, it is worthy to note that the PD-BD comorbidity.. View More»
DOI:
10.4172/2472-1077.1000123