Journal of Clinical and Experimental Ophthalmology
Open Access
ISSN: 2155-9570
ISSN: 2155-9570
Edward L Paul Jr
Paul Vision Institute,
Wilmington, NC
Tanzania
Research Article
A Combined Regimen of Dietary Supplements Containing Omega-3 Fish Oil and Standardized Maqui Berry Extract Improves Dry Eye Related Symptoms in a Pilot Randomized Interventional Clinical Study
Author(s): Edward L Paul Jr, Anisha Patel and Sailaja MachirajuEdward L Paul Jr, Anisha Patel and Sailaja Machiraju
Purpose: To determine if a dietary supplement consisting of a re-esterified triglyceride form of omega-3 fish oil combined with a standardized maqui berry extract is more efficacious for the treatment of dry eye disease than omega-3 fish oil alone.
Methods: This was an institutional review board-approved, single-site, randomized, interventional, placebocontrolled, comparative, pilot clinical study. Patients with mild to moderate dry eye disease (DED) were enrolled and divided into four study groups. Group 1 (O3M) received dietary supplements of a re-esterified triglyceride form of omega-3 fish oil (O3) and a standardized maqui berry extract (M); group 2 (O3) received only the omega-3 supplements; group 3 (M) received only the maqui berry extract supplements; and group 4 received placebo capsules. Thirteen participants aged 26–78 years wi.. View More»