Journal of Horticulture
Open Access
ISSN: 2376-0354
+44-20-4587-4809
ISSN: 2376-0354
+44-20-4587-4809
Cornellius A.M.J.J. Van Den Hondel
Institute Biology Leiden,
Sylviusweg 72, 2333 BE Leiden
England
Research Article
Antimicrobial effects of Indonesian Medicinal Plants Extracts on Planktonic and Biofilm Growth of Pseudomonas aeruginosa and Staphylococcus aureus
Author(s): Sylvia U.T. Pratiwi, Ellen L. Lagendijk, Triana Hertiani, S. de Weert and Cornellius A.M.J.J. Van Den HondelSylvia U.T. Pratiwi, Ellen L. Lagendijk, Triana Hertiani, S. de Weert and Cornellius A.M.J.J. Van Den Hondel
Nowadays it is known that resistance to antibiotics is often caused by biofilm formation of the microbial pathogen. The aim of this study is to evaluate the activity of Indonesian medicinal plants extracts on planktonic growth and biofilm of two bacteria species. Fifty-four (54) ethanol extracts were obtained from a variety of known Indonesian medicinal plants. The growth inhibitory concentration (MIC), effects on biofilm formation and biofilm breakdown, and biofilm architecture in the absence and presence of the extracts by confocal laser-scanning microscopy were performed with Pseudomonas aeruginosa PAO1 and Staphylococcus aureus Cowan I. The extracts showed an inhibitory effect on planktonic growth of these bacteria and also on their biofilm formation. At a concentration as low as 0.12 mg/mL, biofilm formation of P. aeruginosa PAO1 and S. aureus Cowan I is inhibited by 5 plant etha.. View More»
DOI:
10.4172/2376-0354.1000119