Journal of Clinical and Experimental Ophthalmology
Open Access
ISSN: 2155-9570
+44 1223 790975
ISSN: 2155-9570
+44 1223 790975
Ayman A Alkawas
Faculty of Medicine,
11 Osman Ben Afan St. Vilal Al-Game'a, Zagazig, Sharkeya
Egypt
Research Article
Topical Voriconazole Drops With and Without Intrastromal Voriconazole Injection for Treatment of Deep or Resistant Fungal Keratitis
Author(s): Ayman A Alkawas, Basem M Ibrahim, Mohammad M Mahdy, Mona A Shalaby and Kamal AM SolaimanAyman A Alkawas, Basem M Ibrahim, Mohammad M Mahdy, Mona A Shalaby and Kamal AM Solaiman
Purpose: To compare the safety and efficacy of topical voriconazole drops with and without intrastromal voriconazole injection for treatment of deep and/or resistant fungal keratitis.
Patients and methods: A prospective, randomized and comparative study performed on eyes with deep and/or resistant fungal keratitis. Eyes were randomly allocated into two groups according to their order of presentation. Group (A) included eyes treated with intrastromal injection(s) of voriconazole (50 μg/0.1 ml) plus voriconazole eye drops 1% and group (B) included eyes treated with topical voriconazole eye drops 1% alone. Healing of the fungal keratitis was considered as the primary outcome measure. Secondary outcome measures included any reported complication as well as the visual outcome.
Results: Each group included 20 eyes with .. View More»
DOI:
10.4172/2155-9570.1000469