Journal of Clinical and Experimental Ophthalmology
Open Access
ISSN: 2155-9570
ISSN: 2155-9570
Apatsa Lekskul
Thailand
Case Report
Compressive Optic Neuropathy in Thalassemia: A Rare Ophthalmic Consequence of Extramedullary Hematopoiesis
Author(s): Kavin Vanikieti, Pisit Preechawat, Piyaphon Cheecharoen, Apatsa Lekskul, Narong Samipak and Anuchit PoonyathalangKavin Vanikieti, Pisit Preechawat, Piyaphon Cheecharoen, Apatsa Lekskul, Narong Samipak and Anuchit Poonyathalang
Extramedullary hematopoiesis (EMH) is a compensatory physiological proliferation of hematopoietic elements outside the bone marrow as a result of insufficient bone marrow erythropoiesis. It is found in various hematologic disorders (e.g., as sickle cell anemia, thalassemia, myelofibrosis) especially those with chronic anemias. It can affect in any organs, thus producing numerous complications. However, compressive optic neuropathy has been rarely reported. The authors present a case report of an 18-year-old man who was known to be beta thalassemia/Hb E disease with the presentation of compressive optic neuropathy with an excellent response to combination treatment of blood transfusions and low-dose radiotherapy. These findings reflect that beta thalassemia/Hb E or thalassemia intermedia patients should have periodic comprehensive ophthalmic assessment especially those with inadequate .. View More»
DOI:
10.4172/2155-9570.1000549