Journal of Clinical and Experimental Ophthalmology
Open Access
ISSN: 2155-9570
ISSN: 2155-9570
Anja M. Palmowski-Wolfe
FEBO, University Basel University Eye Hospital,
Basel Mittlere Strasse 91, CH-4031 Basel
Switzerland
Research Article
Multifocal Oscillatory Potentials in the ‘Two Global Flash’ mfERG in High and Normal Tension Primary Open-Angle Glaucoma
Author(s): Anja M. Palmowski-Wolfe, Selim Orgül and Margarita G. TodorovaAnja M. Palmowski-Wolfe, Selim Orgül and Margarita G. Todorova
Purpose: In a previous study using the 2 flash mfERG, 90% of normal tension glaucoma (NTG) patients and 85% of high tension primary open angle (POAG) patients could be correctly classified as abnormal while 80% of the control subjects were correctly classified as normal. The purpose of this study was to analyse whether glaucomatous changes contribute to alterations of multifocal oscillatory potentials. Methods: MfERGs were recorded from 20 NTG and 20 POAG patients and compared to those of 20 controls. The mfERG array consisted of 103 hexagons. Each m-sequence step started with a focal flash that could be either dark or light (m-sequence: 2^13, Lmax: 200cd/m2, Lmin: 1cd/m2), followed by two global flashes (Lmax: 200cd/m2) at an interval of ∼26ms. Signals were recorded with a bandpass filter at 10-300Hz. Oscillatory potentials were obtained through offline bandpass filtering .. View More»
DOI:
10.4172/2155-9570.1000167