Autism-Open Access
Open Access

Allison Bechard

Publications

• Review Article
  Modeling Restricted Repetitive Behavior in Animals
  Author(s): Allison Bechard and Mark LewisAllison Bechard and Mark Lewis
  
  Restricted, repetitive behavior is one of the three diagnostic domains for autism spectrum disorders, and commonly observed in a number of other neurodevelopmental disorders. Despite its clinical significance, effective treatments for restricted, repetitive behavior are limited including few, if any, pharmacological interventions with demonstrated efficacy. This is in large measure due to the lack of knowledge of the pathophysiological mechanisms that mediate the development and expression of repetitive behaviors in autism spectrum disorders. Therefore, animal models, particularly those that encompass both lower order and higher order repetitive behaviors, could be particularly useful. Such models could identify various potential etiologies, characterize commonalities in pathophysiology, identify novel potential therapeutic targets, and guide the development and validation of novel tr.. View More»
  DOI: 10.4172/2165-7890.S1-006

  Abstract PDF

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