Journal of Clinical and Experimental Ophthalmology
Open Access
ISSN: 2155-9570
ISSN: 2155-9570
Alistair J Barber
Milton S. Hershey Medical Center,
Hershey PA 17033
Tanzania
Research Article
Measuring Visual Function in Diabetic Retinopathy: Progress in Basic and Clinical Research
Author(s): Zeinab Nasralah, William Robinson, Gregory R Jackson and Alistair J BarberZeinab Nasralah, William Robinson, Gregory R Jackson and Alistair J Barber
Diabetic retinopathy is a common consequence of diabetes mellitus and the leading cause of vision loss in workingage people in the United States. The pathology of this disease is well characterized by microvascular lesions but also includes deficits in visual function, possibly as a consequence of retinal neurodegeneration. Microvasculature changes are clinically detected by fundus examination and used as the primary method of diagnosis, but functional tests may represent alternative endpoints that may be useful in translational research. Components of visual function can be characterized in a variety of different ways including measures of acuity, contrast sensitivity, dark adaptation and a number of electrophysiological parameters of the retina. This review discusses loss of function as measured both in human and animal models of diabetic retinopathy... View More»
DOI:
10.4172/2155-9570.1000306