Autism-Open Access
Open Access
ISSN: 2165-7890
+44 1223 790975
ISSN: 2165-7890
+44 1223 790975
Alessandro Grecucci
Trento
Italy
Research Article
An Abnormal Cerebellar Network in Children with Autistic Spectrum Disorder: A Morphometric Study
Author(s): Alessandro Grecucci, Edoardo Pappaianni and Roma SiugzdaiteAlessandro Grecucci, Edoardo Pappaianni and Roma Siugzdaite
Autism is a neurodevelopmental disorder characterized by poor social abilities, communication deficiency and restricted behavioural patterns. Recently, scholars started to consider the possibility of detecting biological markers for better and faster diagnosing autism. This problem has been approached from different perspectives considering biochemical, neurophysiological, and neuroanatomical markers. Following this perspective, our intent was to investigate whether a structural brain signature of autism can be detected in children by using a whole brain morphological analysis. To this aim, we selected 43 male children with autistic spectrum disorder and 46 male controls, matched for age. Structural brain images (T1 image), intelligence scores (Full IQ, Verbal IQ, Performance IQ), and Autism Diagnostic Observation Schedule (ADOS) scores were considered for analyses. Source-Based Morph.. View More»
DOI:
10.4172/2165-7890.1000178