Journal of Clinical and Experimental Ophthalmology
Open Access
ISSN: 2155-9570
+44 1223 790975
ISSN: 2155-9570
+44 1223 790975
Akash Gupta
Tanzania
Research Article
Fractal Analysis of Peripapillary Vasculature in Eyes with Papilledema Using Optical Coherence Tomography Angiography
Author(s): Ravneet Rai, Bing Chiu, Soshian Sarrafpour, Akash Gupta, Edmund Tsui, David Fell, Sherief Raouf, Nicole K Scripsema, Sarwar Zahid, Sarita Dave, Patricia Garcia, Toco Chui, Richard B Rosen, Rudrani Banik and Joshua A YoungRavneet Rai, Bing Chiu, Soshian Sarrafpour, Akash Gupta, Edmund Tsui, David Fell, Sherief Raouf, Nicole K Scripsema, Sarwar Zahid, Sarita Dave, Patricia Garcia, Toco Chui, Richard B Rosen, Rudrani Banik and Joshua A Young
Background: Papilledema is swelling of the optic nerve secondary to increased intracranial pressure. Optical coherence tomography angiography (OCTA) is a technique that allows for fast and non-invasive imaging of the peripapillary microvasculature. Here, we evaluate a novel way of analyzing OCTA images of eyes with papilledema through the use of fractals to estimate vascular complexity through fractal dimension.
Methods: A retrospective clinical chart review of papilledema patients imaged with OCTA was performed. En face OCT angiograms identifying peripapillary vessels were obtained using a spectral-domain OCT system. Default automated peripapillary scans of 4.5 mm × 4.5 mm diameter were processed with ImageJ. Fractal analysis was performed with Fractalyse software.
Results: Fifty-six eyes with papilledema and 40 .. View More»