Background: The main aim of this report is to assess the changes in the state of health and the nutritional status of individuals, with regards to Ramadan and the effect of this particular diet on the human body. Methods: The relevant clinical information, nutritional status and the changes which occur during Ramadan were recruited for every individual .The follow-up of persons started in the pharmacy shop 10 days prior Ramadan and finish’s 10days afterwards. Biochemical and anthropometrical parameters were evaluated for each person. Results: The following anthropometrical parameters including weight, waist, hip and abdomen perimeter decreased due to fasting in Ramadan. Cholesterol levels decreased during study period. Triglyceride and blood glucose FBS increased. Blood pressure decreased, otherwise heart rate increased. There were statistically changes in those parameters. (p<0,05) Conclusion: Ramadan fasting causes no detrimental effect on health in healthy subjects. In fact, it reduces weight and may cause improvements in cholesterol levels and blood pressure.