Journal of Probiotics & Health

Journal of Probiotics & Health
Open Access

ISSN: 2329-8901

Zahra Keshtmand

Department of Biology, Central Tehran Branch Islamic Azad University, Tehran, Iran

  • Research Article   
    Effect of Probiotics Bifidobacterium lactis And Lactobacillus casei on Sperm Parameters and Expression of Apoptosis BAX and Bcl2 Genes in Streptozotocin- Induced Diabetic Rats
    Author(s): Zahra Keshtmand*

    Diabetes mellitus is a metabolic disorder, which leading to male reproductive disorders. Probiotic bacteria are known to be one of the most effective factors in many diseases. This study aimed to evaluate the effect of probiotics Bifidobacterium lactis and lactobacillus casei on sperm parameters and expression of apoptosis BAX and Bcl2 genes in streptozotocin-induced diabetic rats. In this experimental study, 35 adult male Wistar rats were divided into five control groups, diabetic, diabetic treated with: B.lactis, L.casei and both probiotic B.lactis and L.casei. Diabetic was induced by intraperitoneal injection of streptozotocin at a dose of 60 mg/Kg and Probiotic treatment at a dose of 109 cfu/ml for 56 days was done by gavage. One day after the last gavage, blood glucose, serum insulin, sperm parameters and histology and Histomorphometric of testicular tissue were examined. Also, t.. Read More»
    DOI: 10.35248/2329-8901.21.9.235

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