Journal of Clinical Trials
Open Access

Department of General Medicine and Primary Care, Tokushima University Hospital, Tokushima, Japan

Biography

Dr. Yoshihiro Okura is currently working in Department of General Medicine and Primary Care, Tokushima University Hospital, Tokushima, Japan. He has published numerous research papers and articles in reputed journals and has various other achievements in the related studies. He has extended his valuable service towards the scientific community with his extensive research work. 

Publications

• Research Article   
  Strict Gluten-Restricted Diet Reduces Disease Activity of Rheumatoid Arthritis with Low Anti-Cyclic Citrullinated Peptide Antibodies
  Author(s): Kenji Tani*, Yoshihiro Okura, Shingo Kawaminami, Keisuke Kawahito, Keisuke Kondo, Ryosuke Takahashi, Ryo Tabata, Teruki Shimizu and Harutaka Yamaguchi
  
  Objective: To investigate the efficacy of gluten-restricted diet for the disease activity of Rheumatoid Arthritis (RA) and clinical factors corresponding to the response. Methods: Sixty three patients with active RA were included in this study. At baseline, we gave the patients the information about gluten-free and-contained foods, and asked them to refrain from the daily gluten consumption during the experimental period. Results: The 16-week gluten-restricted diet significantly improved DAS28-CRP and CDAI scores. The percentages of patients achieving DAS28-CRP- and CDAI-defined remission or LDA were significantly increased at Week 16. When the self-reported levels about adherence to the gluten-restricted diet were divided into two categories, a significant improvement in DAS28- CRP, CDAI, and EULAR treatment respo.. View More»
  

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