Journal of Chromatography & Separation Techniques
Open Access
ISSN: 2157-7064
ISSN: 2157-7064
Department of Pharmaceutical Chemistry, S.M.B.T. College of Pharmacy, Dhamangaon, Nashik, India
Research Article
Rapid and Selective Analysis of Vortioxetine Using RP-HPLC
Author(s): Pramila V. Thete*, Manoj R. Kumbhare, Abhijeet V. Patil, Rituja D. Pawar, Gayatri A. Sapkale and Pallavi Dilip Chaudhari
Vortioxetine is a singular antidepressant drug gaining recognition for its capacity in treating principal depressive disease and cognitive dysfunction. Accurate and dependable quantification methods are vital for satisfactory manipulate, pharmacokinetic studies and clinical packages. This work aimed to increase and validate a simple, fast, touchy and Particular Reversed-Segment High-Performance Liquid Chromatography (RP-HPLC) technique for quantifying Vortioxetine in bulk drug and pharmaceutical dosage bureaucracy. The take a look at affords the improvement and validation of an RP-HPLC technique for quantifying Vortioxetine, a remedy used to deal with despair and mood issues. The method involved optimizing chromatographic conditions and evaluating parameters such as linearity, precision, accuracy, specificity, robustness and system suitability. The method demonstrated excellent linear.. View More»
DOI:
10.35248/2157-7064.25.16.621