Journal of Clinical Toxicology

Journal of Clinical Toxicology
Open Access

ISSN: 2161-0495

Yanyun Chen

Yanyun Chen

IR Iran

  • Research Article
    Experimental Oriental Hybrid Lilies (Lilium Hybrids) Poisoning in Cats
    Author(s): Zhaofei Xia, Jianqing Wan, Yanyun Chen, Yuying He and Jinhai YuZhaofei Xia, Jianqing Wan, Yanyun Chen, Yuying He and Jinhai Yu

    The pathophysiology of Oriental hybrid lilies poisoning in cats was studied. Clinically normal eighteen domestic shorthair cats were orally dosed with 0, 1.5, 2.5 g wet weight of homogenate lily flower petals per kg body weight by a nasogastric tube in the study (n=3/sex/dose level). Blood and urine samples were collected before and after dosing. The cats of all treated groups presented anorexia, vomiting, lethargy and depression within 0.5 h after dosing. Serum levels of Alanine transaminase (ALT), Aspartate transaminase (AST), Alkaline phosphatase (ALP), Glutamyl transferase (GGT), Lactate dehydrogenase (LDH), Creatinine (CREA), Blood urea nitrogen (BUN) and Creatine kinase (CK) were increased in all treated groups in a dose-dependent manner. Severe hepatocellular vacuolation was present in the cats of 2.5 g/kg group. Mild and diffuse vacuolar degeneration was observed in the renal .. View More»
    DOI: 10.4172/2161-0495.1000152

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