Anesthesia & Clinical Research
Open Access
ISSN: 2155-6148
ISSN: 2155-6148
Wael Abdel-Razek
Egypt
Research Article
Effectiveness of Dexmedetomidine as an Adjunct Agent for Sedation during ERCP
Author(s): Fatma M Mahmoud, Ashraf S Hasanin and Wael Abdel-RazekFatma M Mahmoud, Ashraf S Hasanin and Wael Abdel-Razek
Objectives: To evaluate dexmedetomidine as an adjunct drug to propofol for sedation during ERCP, and its effects on perfusion index (PI) which could be used as an indicator for analgesia level. Methods: 76 patients ASA (I-III) scheduled for ERCP procedure were randomly classified to either dexmedetomidine/propofol group or propofol group. In dexmedetomidine/propofol group, sedation was induced by dexmedetomidine (0.7 μg/kg) and propofol (50 mg) followed by infusion of dexmedetomidine (0.4 μg/kg/h) and propofol (0.5-1 mg/kg/h). In propofol group, sedation was induced by propofol (50 mg) followed by propofol infusion (0.5-1 mg/kg/h). HR, SBP, DBP, RR, SPO2 and PI were continuously monitored and recorded at the time points (T0 to T8). Results: Comparing dexmedetomidine/propofol group versus propofol group; PI values showed significant increase at T2 to T7 (p˂0.001), HR values show.. View More»
DOI:
10.4172/2155-6148.1000599