Anesthesia & Clinical Research
Open Access
ISSN: 2155-6148
+44 1223 790975
ISSN: 2155-6148
+44 1223 790975
Tomas Drægni
Norway
Research Article
Propofol/Remifentanil Vs Desflurane/Fentanyl in Open
Hemicolectomy Surgery
Author(s): Vinnie Lendvay, Tomas Drægni, Morten Rostrup and Knut Arvid KirkebøenVinnie Lendvay, Tomas Drægni, Morten Rostrup and Knut Arvid Kirkebøen
In a prospective, randomized, parallel-group study the aim was to compare TIVA (total intravenous anesthesia) with propofol / remifentanil and anesthesia with desflurane / fentanyl in open hemicolectomy surgery. 10 patients were randomly assigned each group. The primary endpoint hemodynamic stability was evaluated as number of dose-adjustments due to responses to surgery (hypertension, tachycardia, somatic or autonomic responses). Catecholamine levels, recovery times after anesthesia, postoperative variables and costs were also evaluated. There were no significant differences between the two groups in number of dose-adjustment due to responses to surgery (P = 0.88). One min after skin incision arterial noradrenaline levels were 59 ± 14 pg/ml in the TIVA-group and 262 ± 87 pg / ml in the desflurane-group (P < 0.01). Corresponding adrenaline levels were 16 ± 3 an.. View More»
DOI:
10.4172/2155-6148.1000103