Anesthesia & Clinical Research
Open Access
ISSN: 2155-6148
ISSN: 2155-6148
Tewarux Verawattaganon
Thailand
Research Article
A Comparison of Dexmedetomidine Versus Propofol on Hypotension During Colonoscopy Under Sedation
Author(s): Anchalee Techanivate, Tewarux Verawattaganon, Chuleeporn Saiyuenyong and Pornpatra AreerukAnchalee Techanivate, Tewarux Verawattaganon, Chuleeporn Saiyuenyong and Pornpatra Areeruk
Background: Sedation for colonoscopy with propofol is often associated with decreasing in arterial blood pressure. Dexmedetomidine is a sedative drug with a highly selective alpha2 adrenoreceptor agonist. The direct action on blood vessels causes vasoconstriction and a possible increase of blood pressure. This study evaluates dexmedetomidine on suppression of decrease in blood pressure is compared with propofol for sedation during colonoscopy. Method: Seventy patients with ASA physical status I-III were randomly allocated into two groups to receive either dexmedetomidine or propofol for elective colonoscopy under sedation. Group P patient received 0.5 mcg/kg fentanyl over 5 min, followed by 1 mg/kg propofol. Group D patients was received 1 mcg/kg dexmedetomidine with 0.5 mcg/kg fentanyl over 5 min, followed by 20 mg propofol. The 20 mg propofol was titrated as required to achieve the .. View More»
DOI:
10.4172/2155-6148.1000257