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Histopathological Aspects of Pancreatic Metastases in Renal Cell Carcinoma: Does the Mode of Invasion Permit Limited Resections?
Author(s): Yasutoshi Kimura, Yoshiko Keira, Masafumi Imamura, Tatsuya Ito, Takayuki Nobuoka, Toru Mizuguchi, Naoya Masumori, Tadashi Hasegawa and Koichi HirataYasutoshi Kimura, Yoshiko Keira, Masafumi Imamura, Tatsuya Ito, Takayuki Nobuoka, Toru Mizuguchi, Naoya Masumori, Tadashi Hasegawa and Koichi Hirata
Purpose: To investigate histopathological characteristics, we retrospectively analyzed data from patients who underwent resection of renal cell carcinoma pancreatic metastases (RCC-PMs). Methods: This study included 34 RCC-PM lesions in 13 patients who underwent 15 pancreatic operations. The clinicopathlogical characteristics were analyzed with special emphasis on tumor capsular formation, manner of peritumoral invasion, and presence of lymphovascular invasion. Results: Median duration to onset of RCC-PMs was 101 months from initial nephrectomy. Surgical procedures included distal pancreatectomy in 6 cases, pancreaticoduodenectomy in 4, total pancreatectomy in 1, and limited resections in 6 with two overlapping procedures. No perioperative deaths were encountered. One, three, and five year survival rates after pancreatic resection were 86.2%, 86.2%, and 76.6%, respectively. Of t.. View More»