Anesthesia & Clinical Research
Open Access

Takakuni Abe

Publications

• Research Article
  Continuous Renal Replacement Therapy Improves Septic Shock in Patients Unresponsive to Early Goal-Directed Therapy
  Author(s): Koji Goto, Seigo Hidaka, Takakuni Abe, Ryo Shitomi, Norihisa Yasuda, Shunsuke Yamamoto, Satoshi Hagiwara and Takayuki Noguchi Koji Goto, Seigo Hidaka, Takakuni Abe, Ryo Shitomi, Norihisa Yasuda, Shunsuke Yamamoto, Satoshi Hagiwara and Takayuki Noguchi
  
  Background: Early goal-directed therapy (EGDT) has been shown to improve patient outcomes. Treatment of patients unresponsive to the protocol, however, is difficult and the result is occasionally fatal. Recently, continuous renal replacement therapy (CRRT) has been used to treat acute kidney injury (AKI) to improve survival. We examined the effectiveness of CRRT in treating septic shock patients with concurrent AKI who are not amenable to EGDT. Methods: We studied 17 patients who underwent emergency surgery for intra-abdominal infection; these patients experienced AKI complications and did not respond to EGDT within 6 hrs after intensive care unit (ICU) admission. We treated patients with continuous venovenous hemodiafiltration (CVVHDF; dialysis = 900 ml/hr, filtration = 900 ml/hr, total hemopurification = 1800 ml/hr). We measured mean arter.. View More»
  DOI: 10.4172/2155-6148.1000161

  Abstract PDF

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