Cell & Developmental Biology

Cell & Developmental Biology
Open Access

ISSN: 2168-9296

Stefanie Julia Willmann

Stefanie Julia Willmann

Türkenstrasse 21, 80799 München

  • Research Article
    Unraveling the Myth of Foxa2 in Endocrine Formation of the Pancreatic Lineages
    Author(s): Stefanie Julia WillmannStefanie Julia Willmann

    Diabetes mellitus is a severe disease caused by the autoimmune destruction and/or secreting defects of the β-cells with a global prognosis of 844 million patients in the next 20 years (The World Health Organization). The differences are stated either as T1D (Type1 Diabetes) or T2D (Type 2 Diabetes), focusing on the occurrence of the disease itself and the inheritance either early in life, at the beginning of the adulthood or in adults. Further studies are progressively made in the process of pregnancy, where a specific subset of diabetes appears for the expectant mother. Thus, making the disease itself a complex challenge in the world health population and on focus in the field of Research and Development. The focus is driven by elucidating the different factors in the maturation steps of the pancreatic insulin-secreting β-cell, impairment in this β-cells lead either to.. View More»
    DOI: 10.4172/2168-9296.1000186

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