Cell & Developmental Biology
Open Access

Antigen-Presenting Cells

An antigen-presenting cell (APC) is a cell that displays foreign antigens complexed with major histocompatibility complexes (MHCs) on their surfaces. This process is known as antigen presentation. T-cells may recognize these complexes using their T-cell receptors (TCRs). These cells process antigens and present them to T-cells. Antigen-presenting cells come under two categories: professional and non-professional. Most cells in the body can present antigen to CD8+ T cells via MHC class I molecules and, thus, act as "APCs". To help distinguish between the two types of APCs, those that express MHC class II molecules are often called professional antigen-presenting cells.

Related Journals of Antigen-Presenting Cells

Journal of Vaccines & Vaccination, Journal of Allergy & Therapy, Single Cell Biology, Journal of Carcinogenesis & Mutagenesis, Journal of Leukocyte Biology, Journal of Immunotherapy, Veterinary Immunology and Immunopathology, Cellular Immunology, Journal of Autoimmunity, Microbes and Infection, Journal of General Virology