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Angiology: Open Access

Angiology: Open Access
Open Access

ISSN: 2329-9495

+44 1478 350008

Scott P Forbes

Scott P Forbes

Scott Forbes is a Medical Director at Oxford PharmaGenesis based in Oxford, Oxfordshire. Previously, Scott was a Postdoctoral Fellow at Children's Hospital of Philadelphia

Biography
The endogenous methylarginines, asymmetric dimethylarginine (ADMA) and NG-monomethyl-l-arginine (L-NMMA) regulate nitric oxide (NO) production from endothelial NO synthase (eNOS). Under conditions of tetrahydrobiopterin (BH4) depletion eNOS also generates •O2−; however, the effects of methylarginines on eNOS-derived •O2− generation are poorly understood.

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