Journal of Cell Science & Therapy

Journal of Cell Science & Therapy
Open Access

ISSN: 2157-7013

Samir A. Farghaly

Samir A. Farghaly
Joan and Sanford I. Weill Medical College, The Graduate School of Medical Sciences and The New York Presbyterian Hospital, Weill Cornell Medical Center,
New York

  • Review Article
    Anti- Metastatic Gene Therapy in Patients with Advanced Epithelial Ovarian Cancer (EOC)
    Author(s): Samir A. FarghalySamir A. Farghaly

    Ovarian cancer is the foremost cause of death from gynecological cancer in the developed world. In the USA 27,000 new cases of ovarian cancer and 14,000 deaths are reported in 2010. About 80% of patients with ovarian cancer present with metastatic disease. The overall 5-year survival rate for women with cancer is 30%. The epithelial cells of the ovary constitute 1% of the total ovarian mass but constitute 90% of the ovarian neoplasms. Epithelial ovarian cancer (EOC) spreads initially by direct extensions into adjacent organs, especially the fallopian tubes, uterus and contralateral adnexa and occasionally the rectum, bladder and pelvic side wall. After direct extension, epithelial ovarian cancer frequently disseminates via transcoelmic route, with 70% of patients having peritoneal metastases .. View More»
    DOI: 10.4172/2157-7013.S15-001

    Abstract PDF

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